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• Early ctDNA molecular response captures therapeutic response in the first stage of CCTG BR.36 ctDNA-directed, multi-center phase II study of molecular response adaptive immunotherapy in non-small cell lung cancer

  Study EGAS00001007298

• ADP

  ADP array data, comprised of 2217 samples of Asian ancestry (excluding the Japanese population from ADP). Samples were genotyped on different Illumina or Affy platform.

  Dataset EGAD00010001491

• Paired-end ATAC-seq analysis of the 3D spatially mapped GBM samples.

  Dataset contains 70 paired-end ATAC-seq samples from 8 patients.

  Dataset EGAD00001010311

• Unraveling the transcriptomic profile of utero-tubal lavage fluid of ovarian cancer patients

  mRNA capture seq of uterotubal lavage samples

  Dataset EGAD00001007933

• Whole genome bisulfite sequencing to analyse the molecular response of AML blasts to Aza-treatment.

  Dataset EGAD00001007504

• 4C-Seq datasets of EndoC-bh1

  2 Circular chromosome conformation capture (4C-Seq) datasets of the human beta cell line EndoC-bh1.

  Dataset EGAD00001005210

• TRACERx100 RNAseq

  TRACERx 100: RNAseq data from the first 100 TRACERx tumours (164 tumor regions from 64 patients)

  Dataset EGAD00001004591

• BC WGS Dataset 1

  Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

  Dataset EGAD00001001350

• The Simons Genome Diversity Project: 300 genomes from 142 diverse populations

  Whole genome sequencing of 300 individuals from 142 diverse populations

  Dataset EGAD00001002721

• Gene expression and Cancer

  Dac EGAC00001001727

• CHIP and LOY in AD

  Dac EGAC00001003606

• NHLBI TOPMed: Boston-Brazil Sickle Cell Disease (SCD) Cohort

  This study involves sequencing of patients with a diagnosis of sickle cell disease from Brazil. No exclusionary criteria were employed and any eligible patients that consented to this study were recruited.

  Study phs001599

• A mathematical model of cell-free DNA fragment size reveals cancer-specific fragmentomic patterns

  This study aim to test a mathematical model of cfDNA length distribution across multiple biodiy flulids. It try to investigate biological mechanisms of cfDNA fragmentation and release.

  Study EGAS50000001560

• Multisite_Breast_Cancer_Whole_Genome

  DNA extracted from multiple biopsies taken from different areas of primary breast tumours will be subjected to whole genome sequencing and analysed in order to assess intra-tumour heterogeneity with respect to mutations.

  Study EGAS00001000890

• GENOMIC INSTABILITY IN MISMATCH REPAIR DEFICIENT COLORECTAL CANCER

  Here we performed whole exome sequencing on a series of 47 mismatch repair (MMR) deficient colorectal cancers (CRC) in order to identified key events in tumoral initiation and progression

  Study EGAS00001002477

• Multiple myeloma treated with T-cell redirecting immunotherapies

  Whole Genome Sequencing from patients with multiple myeloma treated with T-Cell redirecting therapies including chimeric antigen receptor T-cells (CAR-T) and Bispecific T-cell Engagers (TCE).

  Study EGAS50000000546

• Growth Hormone (GH) -secreting Pituitary Adenoma

  Data from 12 fresh-frozen somatotropinomas and their corresponding blood samples. Details are given in Valimaki et al. Whole-genome sequencing of Growth Hormone (GH) -secreting Pituitary Adenoma. Provisionally accepted, 2015.

  Study EGAS00001001293

• Whole exome sequencing of preneoplasia lung adenocarcinoma

  Multi-region exome sequencing of 271 pulmonary nodules and matched adjacent lung tissue including lung preneoplasia atypical adenomatous hyperplasia (AAH, N=49), adenocarcinoma in situ (AIS, N=42), minimally invasive adenocarcinoma (MIA, N=37), invasive lung adenocarcinoma (ADC, N=86) and adjacent lung tissues (Normal, N=57).

  Dataset EGAD50000000397

• Single-cell short-read transcriptomes from CH, MDS and AML patients with splicing factor mutations

  Single-cell RNA sequencing from CH (n = 2), MDS (n = 6, MDS02 in 2 replicates) and AML (n = 1, in 2 replicates) samples with mutations in splicing factors (SF3B1 - n = 8, U2AF1 n = 1). cDNA from 10x Genomics 3' V3.

  Dataset EGAD00001011283

• 300BCG trained immunity scRNAseq

  We have paired 39 individuals in 4 conditions: T0_RPMI (baseline, before BCG and without LPS); T0_LPS (before BCG and with LPS); T3m_RPMI (3 months after BCG, without LPS); T3m_LPS (3 months after BCG, with LPS).

  Dataset EGAD00001010055

• RNA-sequencing data from vitamin C experiment

  Fasq-files from 3 unaffected TET2 mutation carriers, 2 mutation carriers diagnosed with lymphoma and 3 family members without TET2 mutation. Time series data collected from 0, 6 and 12 months after daily dose of 1g vitamin C.

  Dataset EGAD00001010009

• Ribodepletion RNA-Seq of 8 samples and polyA RNA-Seq of 22 samples

  Ribodepletion RNA-Seq of 8 samples and polyA RNA-Seq of 22 samples

  Dataset EGAD00001004993

• Single-cell RNA-seq of immune cells from Melanoma tumors (Li et al, 2018)

  Single-cell RNA-seq profiling of immune cells sorted from human Melanoma tumors (and several matching PBMC samples). Contains de-multiplexed FASTQ files per plate (MARS-seq amplification batch, total 204 samples) and also de-multiplexed FASTQ files of single-cell TCRb-seq.

  Dataset EGAD00001004497

• Whole Exome Sequencing syCRC

  Aligned BAM files of whole exome sequencing of 20 syCRCs and 10 normal counterparts. Each sample of 4 patients (S13, S3, S12 and S6) underwent two sequencing rounds.

  Dataset EGAD00001001608

• Multi-region targeted Sequencing data of 10 neuroblastoma cases

  To investigate intratumour heterogeneity and to better understand tumour evolution in neuroblastoma, we have performed a multi-region targeted re-sequencing on a total of 140 samples from 9 primary neuroblastomas (2 low-risk, 1 intermediate-risk and 6 high-risk) and 2 relapsed neuroblastoma.

  Dataset EGAD00001008156

• Pathology and tumor biology DAC

  Dac EGAC00001001287

• Senior Director, Grants and Contracts

  Dac EGAC00001003387

• The evolution of ovarian high grade serous carcinoma from STIC lesions

  We performed Ampliseq on 11 samples on a targeted panel of 17 genes.

  Study EGAS50000000361

• TAVAREC Methylation

  DNA methylation profiles of samples included in the EORTC 26091 TAVAREC trial

  Dataset EGAD00010002289

• CPCG-200PG-ARRAY

  Raw Array data from the CPCGene 200PG study

  Dataset EGAD00010001218

• shallow whole genome sequencing dataset

  shallow whole genome sequencing dataset contains 44 samples. all the samples are early stage high ovarian high grade serous carcinoma.

  Dataset EGAD00001008588

• BS-seq in plasma of CRC patients

  We performed whole genome bisulfite sequencing of plasma DNA in 11 colorectal cancer patients to study the colonic DNA in plasma.

  Dataset EGAD00001004568

• Organoid Derivation Project TGS: Release 1

  Targeted gene sequencing of cancer driver genes to determine the driver mutations present in newly-derived cancer organoid models

  Dataset EGAD00001004368

• whole genome sequencing data of LMS cell lines

  The data set contains bam files aligned using bwa-0.7.8 mem -t 8 -R.

  Dataset EGAD00001003827

• Whole genome SMRT sequencing in the HF-GBM-Tumor-Neurosphere-Xenograft study

  This data set consists of whole genome SMRT sequencing fastqs generated from 2 xenograft samples.

  Dataset EGAD00001002264

• Epi-Tax targeted sequencing

  Sequencing of 350 cancer genes in BC samples from patients treated with either Epirubicin or Paclitaxel monotherapy in the neoadjuvant setting.

  Dataset EGAD00001000812

• Congenital Heart Disease - Pilot

  This pilot study aims to generate pilot data to inform future study designs by resequencing the whole exomes of 10 unrelated individuals diagnosed with Congenital Heart Disease (CHD).

  Dataset EGAD00001000351

• Pathology and tumor biology DAC

  Dac EGAC00001003221

• CDH Asian Head and Neck Angiosarcoma

  Dac EGAC00001003145

• Relapsed and Primary Neuroblastoma DAC

  Dac EGAC00001000373

• Illumina - Population and Medical Genomics Group

  Dac EGAC00001000686

• ICR_Evolutionary Genomics and Modelling

  Dac EGAC00001001050

• RNAseq intra- and extracranial ECs DAC

  Dac EGAC00001001622

• Gene expression and Cancer

  Dac EGAC00001001772

• Neuroblastoma and cell migration DAC

  Dac EGAC00001001965

• Genome-wide data Resande and Swedes

  Dac EGAC00001002627

• INSERM U944 Team Genome and Cancer

  Dac EGAC00001002976

• WGS of eHHV-6B-positive Japanese

  Short-read WGS datasets of 15 eHHV-6B-positive Japanese subjects (Illumina WGS) and long-read WGS datasets of 3 eHHV-6B-positive Japanese subjects with SLE (PacBio 30x HiFi long-read sequencing).

  Study EGAS00001007886

• Esophageal Adenocarcinoma Organoid Genomics

  Single cell RNA-seq (scRNA-seq) of esophageal adenocarcinoma organoids to benchmark variant calling from 10X Genomics scRNA-seq data. Five EAC organoids were subjected to scRNA-seq and two included matched exome data.

  Study EGAS00001005224

• Hi-C in breast healthy, primary cancer and metastatic tissues

  Hi-C libraries have been prepared by enzymatic digestion with MboI restriction enzyme and sonication (Covaris). Illumina single-indexig primers have been use to amplify ligated fragments. Hi-C experiments have been performed on 10 slices (50um thick) of fresh-frozen tissues or 10x10e6 Pleural Effusion cells. Raw paired-end fastq.gz files are provided.

  Dataset EGAD50000000643

• HNF1A haploinsufficiency causes decreased insulin expression, dysregulation of pancreatic progenitor signature genes and affects chromatin accessibility

  HNF1A haploinsufficiency causes decreased insulin expression, dysregulation of pancreatic progenitor signature genes and affects chromatin accessibility

  Dataset EGAD00001011374

• Hi-C of human acute leukemias and healthy donors

  Hi-C of 17 primary samples obtained from human acute leukemias, namely AML, T-ALL and mixed myeloid/lymphoid leukemias with CpG Island Methylator Phenotype (CIMP). Moreover, Hi-C of CD34+ HSPCs from 3 healthy donors are included.

  Dataset EGAD00001011051

• Sequencing of longitudinal glioma pairs

  Clonal evolution drives cancer progression and therapeutic resistance. Recent studies revealed divergent longitudinal trajectories in gliomas, but early molecular traits steering post-treatment cancer evolution remain unclear. We analyzed sequencing data of 544 initial-recurrent adult diffuse glioma pairs to identify genomic and transcriptomic early predictors of tumor evolution in each molecular subtype.

  Dataset EGAD00001009845

• Genomic characterization (through whole-exome sequencing) of bone marrow clonal plasma cells before and after VRD treatment from multiple myeloma patients.

  WES data from clonal pahtologic bone marrow plasma cells of multiple myeloma patients. From each patient there are three samples, pathologyc bone marrow plasma cells at diagnosis, pathologyc bone marrow plasma cells after VRD treatment and T lymphocytes as germline control. There are 14 patients in total

  Dataset EGAD00001006302

• Epigenomics and Single-cell Sequencing Define Cellular Heterogeneity in Langerhans Cell Histiocytosis

  Epigenomic and transcriptomic analysis of Langerhans cell histiocytosis (LCH) biopsies. Single-cell RNA-seq (10x Genomics) of seven LCH biopsies. ATAC-seq data from four sorted cell populations (in duplicate) from one LCH biopsy.

  Dataset EGAD00001005280

• BAM files of Roma and non-Roma Romanians

  BAM files (Illumina HiSeq 2000) with whole genome sequencing data of 49 individuals of European/Romanian descent, and 50 individuals of Roma (Romani/Rroma) ethnic background from Romania.

  Dataset EGAD00001004981

• Whole genome sequencing on HiSeq platform of melanocytic nevi and normal sample pairs from 14 cases

  Aligned, merged and deduplicated BAM files from HiSeq whole genome sequencing of 28 samples: matched tumour-normal pairs from 14 melanocytic nevi cases

  Dataset EGAD00001004474

• Pilot study Pilocytic Astrocytoma ICGC PedBrain, whole genome sequencing of 5 tumors and matched blood

  Pilot study Pilocytic Astrocytoma ICGC PedBrain, whole genome sequencing of 5 tumors and matched blood

  Dataset EGAD00001000271

• EGAD00000000045

  Genomic sequencing and transcriptome shotgun sequencing of a metastatic tumour and its recurrence after drug therapy in a single patient

  Dataset EGAD00000000045

• Paired ONT and downsampled Illumina cfDNA dataset

  Dac EGAC00001002860

• Tumor-Normal matched colon adenomas and carcinomas

  Dac EGAC00001003248

• Microenvironment in lymphoma pathogenesis and therapy - DAC

  Dac EGAC00001003228

• Leucocyte eQTLs in autoimmune disease and health

  Dac EGAC00001000338

• Multiple esclerosis and mixed microbial infections DAC

  Dac EGAC00001000892

• 16S rRNA gene amplification and maternal factors DAC

  Dac EGAC00001000931

• Pathology and tumor biology

  Dac EGAC00001001923

• Sarcoma biology and genomics data access commitee

  Dac EGAC00001002609

• Sarcoma biology and genomics data access committee

  Dac EGAC00001002610

• Pheochromocytoma and paraganglioma single nuclei RNA-seq

  Dac EGAC00001002657

• Computational Cancer Genomics and Tumor Evolution Group

  Dac EGAC00001002722

• MSAT and JMS Data Access Committee

  Dac EGAC00001002734

• Human islet sQTL and eQTL DAC

  Dac EGAC00001002796

• Genomics and Oncogenesis of Pediatric Brain Tumors

  Dac EGAC00001003123

• DAC Bone and soft tissue tumor pathology

  Dac EGAC50000000228

• RNASeq Javelin head and neck 100

  Study EGAS00001007497

• Access to public datasets in the EGA

  Dac EGAC00001000514

• WES of Multiple myeloma/MGUS cases (germline) - Fastq files

  WXS - Exome capture using the Twist Human Core Exome Kit on germline DNA, paired-end (2x100bp) sequencing on a NovaSeq system. Number of samples: 295

  Dataset EGAD50000001799

• Nanopore targeted sequencing of the CFTR gene in Moroccan patients with suspected cystic fibrosis

  This dataset contains fastq files sequencing with Oxford Nanopore (MK1C)

  Dataset EGAD50000002062

• PBAT sequencing of human embryonic stem cells

  To assess the DNA methylation landscape of naïve human embryonic stem cells derived from ERKi or control blastocysts using PXGL or UXGL media.

  Dataset EGAD50000001475

• Paired-end Whole Exome-seq analysis of the 3D spatially mapped GBM samples.

  Dataset contains 50 paired-end Whole Exome sequencing samples from 3 patients. 3 normal blood samples are also included.

  Dataset EGAD00001010289

• Melanoma transcriptome profiling

  This dataset includes transcriptome profiling of 68 early-passage metastatic melanoma cell lines. The data are provided as paired-end RNA seq fastq files.

  Dataset EGAD00001006270

• Melanoma microRNA profiling

  This dataset includes microRNA profiling of 61 early-passage metastatic melanoma cell lines. The data are provided as single-end small RNA seq fastq files.

  Dataset EGAD00001006269

• Pancreatic organoid - case samples

  This dataset contains 31 pancreatic organoid samples used in the 'organoid data of pancreatic cancers ' study

  Dataset EGAD00001004528

• HDAC inhibitor quisinostat in synovial sarcoma cell lines

  An RNA Seq study of the effects of HDAC inhibitor Quisinostat on six different synovial sarcoma cell lines

  Dataset EGAD00001003810

• Bone Cancer - Rare Types Whole Genome

  We propose to definitively characterise the somatic genetics of a selection of rare bone cancers through generation of comprehensive catalogues of somatic mutations by high coverage genome sequencing.

  Dataset EGAD00001000785

• Exome sequencing of Bilateral Anophthalmia cases- Pilot Study

  This pilot study aims to generate pilot data to inform future study designs by resequencing the whole exomes of 10 unrelated individuals diagnosed with Bilateral Anophthalmia.

  Dataset EGAD00001000348

• A108757B

  Whole genome sequencing for single cells for library A108757B 1644 cells; filetype=bam

  Dataset EGAD00001007086

• Human primary and metastatic colorectal cancer (CRC) samples

  Dac EGAC00001002954

• NCCS-NSCLC-ITH2 project leader and principal investigator

  Dac EGAC00001003152

• Department of Gastroenterology and Hepatology Data Access Committee

  Dac EGAC00001003361

• Shanghai Institute of Endocrine and Metabolic Diseases

  Dac EGAC00001000677

• KUL Research group Molecular Bacteriology and Beneo Orafti.

  Dac EGAC00001000706

• Primary tumor and metastatic breast cancer data access

  Dac EGAC00001001687

• DKFZ OE0436 and UNI-Klinikum Heidelberg DAC

  Dac EGAC00001001904

• Haematopoietic stem cells and malignancies Data Access Comittee

  Dac EGAC00001002410

• DAC Genome-wide array data Tunisia and Morocco

  Dac EGAC00001002770

• France

  French cases and controls

  Dataset EGAD00010002023

• Belgium

  Belgian cases and controls

  Dataset EGAD00010002022

• Finland

  Finnish cases and controls

  Dataset EGAD00010002020

• Genomics and Oncogenesis of Pediatric Brain Tumors

  Dac EGAC00001003200