-
B cell receptor silencing reveals origin and dependencies of high-grade B cell lymphomas with MYC and BCL2 rearrangements
Study
EGAS50000001047
-
Expanding the SPTBN1 Spectrum: A Case of Neurodevelopmental Disorder with GI and Musculoskeletal Involvement
Study
EGAS50000001213
-
German early-onset prostate cancer cohort of the Pan-Prostate Cancer Genome (PPCG) project
Study
EGAS00001003373
-
Ancient Yakuts genomes and metagenomes
Dataset
EGAD50000001903
-
METABRIC
Study
EGAS00000000083
-
Lindsey E. Jones et al. Patient-derived cells from recurrent tumors that model the evolution of IDH-mutant glioma. Neuro-Oncology Advances, 2020. We established robust, versatile, and well-characterized Patient Derived Cells (PDC) of an IDH1-mutant astrocytoma and an IDH1-mutant oligodendroglioma that represents defined evolutionary stages of chemotherapy-induced hypermutation. The PDCs retain tumor subtype defining features over time as well as classic hallmarks of cancer, including anchorage independent growth and cell immortality. The integrated phylogenies composed of PDCs,single-cell-derived PDCs, patient-derived xenografts, and corresponding spatiotemporal tumor tissue samples also provide new insight into the clonality, evolutionary pattern, and immense mutational load of hypermutated IDH mutant gliomas.
Study
EGAS00001003992
-
OpACIN-neo – A Multicenter Phase 2 Study to identify the Optimal neo-Adjuvant Combination scheme of Ipilimumab and Nivolumab – Whole exome sequencing
Study
EGAS00001004832
-
Automated machine-learning approach for next generation profiling of sequence alterations, mutation burden, microsatellite instability, and structural variants in human cancers
Study
EGAS00001005556
-
OpACIN-neo – A Multicenter Phase 2 Study to identify the Optimal neo-Adjuvant Combination scheme of Ipilimumab and Nivolumab – RNA sequencing
Study
EGAS00001004833
-
ACT-Discover: identifying karyotype heterogeneity in pancreatic cancer evolution using ctDNA
Study
EGAS00001007077
-
Effects of 2DG, Galactose, or Oligomycin on the epigenome remodeling induce by T cells activation.
Study
EGAS00001007115
-
Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions(H021/INF)
Study
EGAS00001006939
-
UK10K NEURO IOP COLLIER
Study
EGAS00001000121
-
UK10K NEURO GURLING
Study
EGAS00001000225
-
Therapeutic Resistance to PI3K-alpha Inhibitors
Study
EGAS00001000991
-
Genomic analysis of patient-derived xenograft models reveals intratumor-heterogeneity in endometrial cancer and can predict tumor growth inhibition with talazoparib
Study
EGAS00001004666
-
Histological Transformation and Progression in Follicular Lymphoma: a Clonal Evolution Study
Study
EGAS00001001709
-
Foundation Medicine Genomic Data Used to Identify Prognostic Markers and Fusion Genes in Multiple Myeloma
Study
EGAS00001002874
-
Scottish High Grade Serous Ovarian Cancer
Study
EGAS00001004410
-
Germline elongator mutations in sonic hedgehog medulloblastoma
Study
EGAS00001004126
-
Gene expression-based prediction of pazopanib efficacy in sarcoma (HIPO, H021)
Study
EGAS00001005836
-
Evolution and clinical impact of genetic epistasis within EGFR-mutant lung cancers
Study
EGAS00001002604
-
Identifying transcriptional programs underlying anti-EGFR small molecule response and resistance with TraCe-seq
Study
EGAS00001005405
-
Characterization of Cell Free Plasma Methyl-DNA From Xenografted Tumors to Guide the Selection of Diagnostic Markers for Early-Stage Cancers
Study
EGAS00001006175
-
Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets
Study
EGAS00001006059
-
HCA_Thymus_Disease_DiGeorge_Transplant_RNA
Study
EGAS00001004025
-
High-resolution testing of ctDNA dynamics predicts survival in metastatic NSCLC
Study
EGAS00001006703
-
Influence of Genomic Landscape on Cancer Immunotherapy for Newly Diagnosed Ovarian Cancer: Biomarker Analyses from the IMagyn050 Randomized Clinical Trial
Study
EGAS00001006838
-
TK-EPN862 - Patient-dervied xenograft model of Posterior Fossa A Ependymoma - RNAseq
Study
EGAS00001006844
-
Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
Study
EGAS00001007362
-
APOBEC mutagenesis is a common process in normal human small intestine
Dataset
EGAD00001008764
-
The Haemgen RBC study
Study
EGAS00000000132
-
Warm_autopsy__mutational_signatures_and_clonal_units
Study
EGAS00001002216
-
SABE_1171_WGS_GVCF_IDX
Dataset
EGAD00001008203
-
CRCbiome: Gut metagenome of Norwegian screening participants using FIT sampling
Study
EGAS50000000170
-
Small RNA sequencing of endometrial cancer patients with samples collected prior to diagnosis and controls
Dataset
EGAD50000000391
-
Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort
Study
EGAS00001000096
-
Mutational dynamics of triple negative breast cancer over neoadjuvant chemotherapy treatment reveal frequent whole genome duplication events
Study
EGAS00001008261
-
Sensitive and robust liquid biopsy-based detection of PIK3CA mutations
Study
EGAS00001004940
-
Dissociation of solid tumour tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress responses
Study
EGAS00001003753
-
Molecular_characterization_of_invasive_lobular_carcinoma
Study
EGAS00001000292
-
Genome_Diversity_in_Africa_Project___GemCode_libraries
Study
EGAS00001001589
-
Clinical and Molecular Investigation of Familial CEBPA-mutated Acute Myeloid Leukaemia
Study
EGAS00001000949
-
Conjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study
Study
EGAS00001001516
-
Genome_Diversity_in_Africa_Project__Benin
Study
EGAS00001001688
-
Multi-omics data of 1000 Inflammatory Bowel Disease patients
Study
EGAS00001002702
-
UK10K RARE COLOBOMA
Study
EGAS00001000127
-
UK10K_OBESITY_SCOOP
Study
EGAS00001000124
-
Clinical outcomes in ctDNA-positive urothelial carcinoma patients treated with adjuvant immunotherapy
Study
EGAS00001004997
-
RNA_Seq_in_Patients_with_Primordial_Dwarfism
Study
EGAS00001000283
-
Defective Homologous Recombination DNA Repair as Therapeutic Target in Advanced-Stage Chordoma (HIPO_021)
Study
EGAS00001002720
-
RNA-seq of DF149 cells – a patient-derived xenograft model of ascites-derived, homologous recombination repair-proficient, high-grade serous ovarian carcinoma – cultured in vitro and isolated after 8 hours treatment with DMSO control (3 x biological replicates) and 2.5 µM CBL0137 (3 x biological replicates)
Study
EGAS00001006662
-
Exploring high-throughput drug sensitivity testing in neuroblastoma cell lines and patient-derived tumor organoids in the era of precision medicine
Study
EGAS00001007160
-
Discrepancies in Tumour Mutation Burden (TMB) reporting from sequential Endobronchial ultrasound trans bronchial needle aspiration (EBUS TBNA) samples within single lymph node stations
Study
EGAS00001007484
-
Plasma MicroRNA Signatures of Aging
Study
EGAS00001008117
-
Whole Genome Sequencing and Variant Calling for Autism Families
Dataset
EGAD00001008452
-
A body map of somatic mutagenesis in morphologically normal human tissues
Dataset
EGAD00001007859
-
Transcriptome of CD4+ T cells and CD8+ T cells in glioblastoma multiforme
Study
EGAS50000000156
-
MediMer: A versatile do-it-yourself peptide-receptive MHC class I multimer platform for tumor neoantigen-specific T cell detection
Study
EGAS50000000065
-
All you need to know about our new DAC Portal v2
Blog
new-dac-portal-v2
-
RNA_seq_analysis_of_transcriptome_variation_with_human_ESC_subclones
Study
EGAS00001001655
-
The subclonal architecture of metastatic breast cancer: Results from a prospective community-based rapid autopsy program 'CASCADE'
Study
EGAS00001002153
-
DNA methylomes of monozygotic twins clinically discordant for multiple sclerosis
Study
EGAS00001003147
-
PSCP_bisulphite_analysis_in_hESCs
Study
EGAS00001001625
-
PSCP_mutation_analysis_in_hESCs
Study
EGAS00001001561
-
Pediatric Papillary Thyroid Carcinoma RNA-Seq
Study
EGAS00001005182
-
Single cell genomic variation induced by mutational processes in cancer
Study
EGAS00001006343
-
TNBC ctDNA Targeted Panel
Study
EGAS00001006937
-
TRACERx NSCLC - Whole exome multiregion sequencing data from the 421 cohort
Dataset
EGAD00001009825
-
PanCuRx Translational Research Initiative
Study
EGAS00001002543
-
Whole transcriptome RNA sequencing as comprehensive diagnostic tool for acute myeloid leukemia.
Study
EGAS00001003096
-
Molecularly matched targeted therapies plus radiotherapy in patients with newly diagnosed glioblastoma without MGMT promoter hypermethylation (N2M2/NOA-20 phase I/IIa umbrella trial)
Study
EGAS00001008033
-
sn-RNAseq profiling of the impact of a cytokine storm model in human cardiac organoids
Study
EGAS00001005174
-
Beyond BRCA deficiency: Clinical and molecular predictors of survival in patients with BRCA-deficient tubo-ovarian high-grade serous carcinoma
Study
EGAS00001008059
-
Covid19 Gene expression
Dataset
EGAD00001010185
-
DDD DATAFREEZE 2013-12-18: 1133 trios - VCF files (Ref: DDD Nature 2015)
Dataset
EGAD00001001355
-
DDD DATAFREEZE 2013-12-18: 1133 trios - exome sequence BAM files (Ref: DDD Nature 2015)
Dataset
EGAD00001001114
-
Robust detection of translocations in lymphoma FFPE samples using Targeted Locus Capture-based sequencing
Study
EGAS00001004760
-
Capturing sex-specific and infertility-linked effects of assisted reproductive technologies on the cord blood DNA methylome
Study
EGAS00001006643
-
Solve-RD_ITHACA_cohort-1_DF1+2_V1
Dataset
EGAD00001009770
-
Koean HCC exome sequencing
Dataset
EGAD00001005361
-
covid19 RNASeq raw fastq read
Dataset
EGAD00001010079
-
Irish Covid19 RNASeq Alignment Data files
Dataset
EGAD00001010099
-
DDD DATAFREEZE 2013-12-18: 1133 trios - README, family trios, phenotypes, validated DNMs (Ref: DDD Nature 2015)
Dataset
EGAD00001001413
-
Institut Curie Neuroblastoma Whole Genome Sequencing Diagnosis Relapse
Dataset
EGAD00001001356
-
A_study_of_the_genetic_basis_of_evation_by_Acute_Myeloid_Leukaemia_of_Graft_vs_Leukaemia_effects_after_allogeneic_bone_marrow_transplantation
Study
EGAS00001000145
-
The BC Cancer Agency's Personalized Onco-Genomics Project
Study
EGAS00001001159
-
Genomic Profiling Reveals Spatial Intra-tumour Heterogeneity in Follicular Lymphoma
Study
EGAS00001002492
-
Transcriptomic analysis of liver CD8+ T cells
Study
EGAS00001006885
-
Covid19 WGS variants analysis
Dataset
EGAD00001010138
-
GCAT| WGS BAM V1
Dataset
EGAD00001008202
-
Irish Covid19 WGS Raw Reads
Dataset
EGAD00001010186
-
Characterization of individual foci of multicentric/multifocal breast cancer using targeted next generation sequencing
Dataset
EGAD00001000624
-
Effect of ETS2 modulation on chromatin accessibility and enhancer activity in inflammatory (TPP) macrophages
Study
EGAS50000000109
-
Small molecule inhibitors of LOXL synergize with 5-AZA to restore erythropoiesis in myeloid neoplasms
Study
EGAS00001006174
-
Targeted_sequencing_of_genes_recurrently_mutated_in_AML
Study
EGAS00001000408
-
Prognostic and therapeutic significance of leukemia subtypes and minimal residual disease measurements in pediatric acute lymphoblastic leukemia treated with contemporary risk-directed trial: a cohort study
Study
EGAS00001004739
-
Exome sequencing reveals pathogenic variants in known and novel candidate genes for severe sperm motility disorders
Study
EGAS00001005018
-
Recurrent DNMT3B gene rearrangements are associated with unfavorable outcome in dicentric (9;20)-positive pediatric BCP-ALL
Study
EGAS00001007383
-
The British Autozygosity Populations BioResource (2022-04-26)
Dataset
EGAD00001008736